Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression

Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression

Summary: Background: Osteoarthritis (OA) is the most common joint disease and is the leading cause of chronic disability among older people. Chondrocyte death and extracellular matrix (ECM) degradation was involved in OA pathogenesis. Ferroptosis was an iron-dependent cell death associated with per...

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Bibliographic Details
Main Authors: Yu Miao, Yiwei Chen, Feng Xue, Kexin Liu, Bin Zhu, Junjie Gao, Junhui Yin, Changqing Zhang, Guangyi Li
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:EBioMedicine
Subjects:
Osteoarthritis
Ferroptosis
Chondrocyte
GPX4
Extracellular matrix
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422000317

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http://www.sciencedirect.com/science/article/pii/S2352396422000317

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