Defining the timeline of periostin upregulation in cardiac fibrosis following acute myocardial infarction in mice

Abstract After myocardial infarction (MI), the heart's reparative response to the ischemic insult and the related loss of cardiomyocytes involves cardiac fibrosis, in which the damaged tissue is replaced with a fibrous scar. Although the scar is essential to prevent ventricular wall rupture in...

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Bibliographic Details
Main Authors: Hadas Gil, Matan Goldshtein, Sharon Etzion, Sigal Elyagon, Uzi Hadad, Yoram Etzion, Smadar Cohen
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-26035-y