Electrochemical DNA Sensor for Sensitive BRCA1 Detection Based on DNA Tetrahedral-Structured Probe and Poly-Adenine Mediated Gold Nanoparticles

BRCA1 is the biomarker for the early diagnosis of breast cancer. Detection of BRCA1 has great significance for the genetic analysis, early diagnosis and clinical treatment of breast cancer. In this work, we developed a simple electrochemical DNA sensor based on a DNA tetrahedral-structured probe (TS...

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Bibliographic Details
Main Authors: Dezhi Feng, Jing Su, Guifang He, Yi Xu, Chenguang Wang, Mengmeng Zheng, Qiuling Qian, Xianqiang Mi
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/10/7/78