Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4
<p>Abstract</p> <p>Background</p> <p>Chemokine SDF1α and its unique receptor CXCR4 have been implicated in organ-specific metastases of many cancers including breast cancer. Hypoxia is a common feature of solid tumors and is associated with their malignant phenotype. We...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-05-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/10/225 |