A mosaic influenza virus-like particles vaccine provides broad humoral and cellular immune responses against influenza A viruses

Abstract The development of a universal influenza vaccine to elicit broad immune responses is essential in reducing disease burden and pandemic impact. In this study, the mosaic vaccine design strategy and genetic algorithms were utilized to optimize the seasonal influenza A virus (H1N1, H3N2) hemag...

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Bibliographic Details
Main Authors: Xuejie Liu, Tianyi Zhao, Liangliang Wang, Zhuolin Yang, Chuming Luo, Minchao Li, Huanle Luo, Caijun Sun, Huacheng Yan, Yuelong Shu
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00728-5