The transcription factor HLH-26 controls probiotic-mediated protection against intestinal infection through up-regulation of the Wnt/BAR-1 pathway.

Probiotics play a critical role in the control of host intestinal microbial balance, protecting the host from gastrointestinal pathogens, modulating the host immune response, and decreasing host susceptibility to infection. To understand the mechanism underlying the protective effect of probiotics a...

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Bibliographic Details
Main Authors: Yu Sang, Jie Ren, Alejandro Aballay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001581