Astragaloside IV Attenuates Glutamate-Induced Neurotoxicity in PC12 Cells through Raf-MEK-ERK Pathway.

Astragaloside IV (AGS-IV) is a main active ingredient of Astragalus membranaceus Bunge, a medicinal herb prescribed as an immunostimulant, hepatoprotective, antiperspirant, a diuretic or a tonic as documented in Chinese Materia Medica. In the present study, we employed a high-throughput comparative...

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Bibliographic Details
Main Authors: Rongcai Yue, Xia Li, Bingyang Chen, Jing Zhao, Weiwei He, Hu Yuan, Xing Yuan, Na Gao, Guozhen Wu, Huizi Jin, Lei Shan, Weidong Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4427284?pdf=render