Evaluation of micelles incorporated into thermosensitive hydrogels for intratumoral delivery and controlled release of docetaxel: A dual approach for in situ treatment of tumors

The in situ gelling hybrid hydrogel system has been reported to effectively concentrate chemotherapeutic drugs at the tumor site and sustain their release for a long period. DTX-micelles (docetaxel-loaded mixed micelles) are able to increase the solubility of DTX in water, and then a high drug loadi...

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Bibliographic Details
Main Authors: Meng Xu, Yanhua Mou, Mingming Hu, Wenxiang Dong, Xitong Su, Rongxia Wu, Peng Zhang
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Asian Journal of Pharmaceutical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087618302186