Mrs4 loss of function in fungi during adaptation to the cystic fibrosis lung

Mrs4 loss of function in fungi during adaptation to the cystic fibrosis lung

ABSTRACT The genetic disease cystic fibrosis (CF) frequently leads to chronic lung infections by bacteria and fungi. We identified three individuals with CF with persistent lung infections dominated by Clavispora (Candida) lusitaniae. Whole-genome sequencing analysis of multiple isolates from each i...

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Bibliographic Details
Main Authors: Daniel Murante, Elora G. Demers, Tania Kurbessoian, Marina Ruzic, Alix Ashare, Jason E. Stajich, Deborah A. Hogan
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mBio
Subjects:
cystic fibrosis
fungi
iron
Mrs4
Clavispora lusitaniae
Exophiala dermatitidis
Online Access:https://journals.asm.org/doi/10.1128/mbio.01171-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01171-23

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