p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes

While current thinking posits that insulin signaling to glucose transporter 4 (GLUT4) exocytic translocation and glucose uptake in skeletal muscle and adipocytes is controlled by phosphorylation-based signaling, many proteins in this pathway are acetylated on lysine residues. However, the importance...

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Bibliographic Details
Main Authors: Vitor F. Martins, Samuel A. LaBarge, Alexandra Stanley, Kristoffer Svensson, Chao-Wei Hung, Omer Keinan, Theodore P. Ciaraldi, Dion Banoian, Ji E. Park, Christina Ha, Byron Hetrick, Gretchen A. Meyer, Andrew Philp, Larry L. David, Robert R. Henry, Joseph E. Aslan, Alan R. Saltiel, Carrie. E. McCurdy, Simon Schenk
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-01-01
Series:JCI Insight
Subjects:
Endocrinology
Muscle biology
Online Access:https://doi.org/10.1172/jci.insight.141344

Internet

https://doi.org/10.1172/jci.insight.141344

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