Extrahepatic Bile Duct Organoids as a Model to Study Ischemia/Reperfusion Injury During Liver Transplantation

Extrahepatic Bile Duct Organoids as a Model to Study Ischemia/Reperfusion Injury During Liver Transplantation

Biliary complications are still a major cause for morbidity and mortality after liver transplantation (LT). Ischemia/reperfusion injury (IRI) leads to disruption of the biliary epithelium. We introduce a novel model to study the effect of IRI on human cholangiocytes using extrahepatic cholangiocyte...

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Bibliographic Details
Main Authors: P. Kreiner, E. Eggenhofer, L. Schneider, C. Rejas, M. Goetz, N. Bogovic, S. M. Brunner, K. Evert, H. J. Schlitt, E. K. Geissler, H. Junger
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Transplant International
Subjects:
regenerative medicine
organoids
liver transplant
cholangiopathy
cholangiocyte organoids
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13212/full

Internet

https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13212/full

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