ER stress proteins in autoimmune and inflammatory diseases

Over the past two decades, heat shock proteins (HSPs) have been implicated in inflammatory responses and autoimmunity. HSPs were originally believed to maintain protein quality control in the cytosol. However, they also exist extracellularly and appear to act as inflammatory factors. Recently, a gro...

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Bibliographic Details
Main Authors: Daisuke eMorito, Kazuhiro eNagata
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00048/full