Cyclodextrin Derivatives as Promising Solubilizers to Enhance the Biological Activity of Rosmarinic Acid

Cyclodextrin Derivatives as Promising Solubilizers to Enhance the Biological Activity of Rosmarinic Acid

Rosmarinic acid (RA) is a natural antioxidant with neuroprotective properties; however, its preventive and therapeutic use is limited due to its slight solubility and poor permeability. This study aimed to improve RA physicochemical properties by systems formation with cyclodextrins (CDs): hydroxypr...

Full description

Bibliographic Details
Main Authors: Anna Stasiłowicz-Krzemień, Natalia Rosiak, Anita Płazińska, Wojciech Płaziński, Andrzej Miklaszewski, Ewa Tykarska, Judyta Cielecka-Piontek
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
rosmarinic acid
cyclodextrins
neurodegeneration
solubility
permeability
blood–brain barrier
Online Access:https://www.mdpi.com/1999-4923/14/10/2098

Internet

https://www.mdpi.com/1999-4923/14/10/2098

Similar Items