Reduction of liver macrophage transduction by pseudotyping lentiviral vectors with a fusion envelope from <it>Autographa californica </it>GP64 and Sendai virus F2 domain
<p>Abstract</p> <p>Background</p> <p>Lentiviral vectors are well suited for gene therapy because they can mediate long-term expression in both dividing and nondividing cells. However, lentiviral vectors seem less suitable for liver gene therapy because systemically admi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-10-01
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| Series: | BMC Biotechnology |
| Online Access: | http://www.biomedcentral.com/1472-6750/9/85 |