Reduction of liver macrophage transduction by pseudotyping lentiviral vectors with a fusion envelope from <it>Autographa californica </it>GP64 and Sendai virus F2 domain

Reduction of liver macrophage transduction by pseudotyping lentiviral vectors with a fusion envelope from <it>Autographa californica </it>GP64 and Sendai virus F2 domain

<p>Abstract</p> <p>Background</p> <p>Lentiviral vectors are well suited for gene therapy because they can mediate long-term expression in both dividing and nondividing cells. However, lentiviral vectors seem less suitable for liver gene therapy because systemically admi...

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Bibliographic Details
Main Authors:	Hiralall Johan K, van Til Niek P, Markusic David M, Elferink Ronald, Seppen Jurgen
Format:	Article
Language:	English
Published:	BMC 2009-10-01
Series:	BMC Biotechnology
Online Access:	http://www.biomedcentral.com/1472-6750/9/85

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