Analysis of the Single-Cell Heterogeneity of Adenocarcinoma Cell Lines and the Investigation of Intratumor Heterogeneity Reveals the Expression of Transmembrane Protein 45A (TMEM45A) in Lung Adenocarcinoma Cancer Patients

Analysis of the Single-Cell Heterogeneity of Adenocarcinoma Cell Lines and the Investigation of Intratumor Heterogeneity Reveals the Expression of Transmembrane Protein 45A (TMEM45A) in Lung Adenocarcinoma Cancer Patients

Intratumoral heterogeneity (ITH) is responsible for the majority of difficulties encountered in the treatment of lung-cancer patients. Therefore, the heterogeneity of NSCLC cell lines and primary lung adenocarcinoma was investigated by single-cell mass cytometry (CyTOF). First, we studied the single...

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Bibliographic Details
Main Authors: Patrícia Neuperger, József Á. Balog, László Tiszlavicz, József Furák, Nikolett Gémes, Edit Kotogány, Klára Szalontai, László G. Puskás, Gábor J. Szebeni
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
non-small cell lung cancer
adenocarcinoma
intra-cell-line heterogeneity
intratumor heterogeneity
TMEM45A
Online Access:https://www.mdpi.com/2072-6694/14/1/144

Internet

https://www.mdpi.com/2072-6694/14/1/144

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