Differential role of glucocorticoid receptor based on its cell type specific expression on tumor cells and infiltrating lymphocytes

Differential role of glucocorticoid receptor based on its cell type specific expression on tumor cells and infiltrating lymphocytes

Background: The glucocorticoid receptor (GR) is frequently expressed in breast cancer (BC), and its prognostic implications are contingent on estrogen receptor (ER) status. To address conflicting reports and explore therapeutic potential, a GR signature (GRsig) independent of ER status was developed...

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Bibliographic Details
Main Authors: V.P. Snijesh, Vidya P. Nimbalkar, Sharada Patil, Savitha Rajarajan, C.E. Anupama, S Mahalakshmi, Annie Alexander, Ramu Soundharya, Rakesh Ramesh, B.S. Srinath, Mohit Kumar Jolly, Jyothi S. Prabhu
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Translational Oncology
Subjects:
Glucocorticoid receptor
Gene signature
Proliferation
Tumor microenvironment
Epithelial to mesenchymal transition
Prognosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324000846

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http://www.sciencedirect.com/science/article/pii/S1936523324000846

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