Whole-Exome Screening and Analysis of Signaling Pathways in Multiple Endocrine Neoplasia Type 1 Patients with Different Outcomes: Insights into Cellular Mechanisms and Possible Functional Implications

Whole-Exome Screening and Analysis of Signaling Pathways in Multiple Endocrine Neoplasia Type 1 Patients with Different Outcomes: Insights into Cellular Mechanisms and Possible Functional Implications

Multiple endocrine neoplasia type 1 (MEN1) is a syndrome characterized by tumors in multiple organs. Although being a dominantly inherited monogenic disease, disease phenotypes are unpredictable and differ even among members of the same family. There is growing evidence for the role of modifier gene...

Full description

Bibliographic Details
Main Authors: Anna Skalniak, Małgorzata Trofimiuk-Müldner, Marcin Surmiak, Justyna Totoń-Żurańska, Agata Jabrocka-Hybel, Alicja Hubalewska-Dydejczyk
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
multiple endocrine neoplasia type 1 (MEN1)
whole-exome screening
pituitary tumors
adrenocortical tumors
Online Access:https://www.mdpi.com/1422-0067/25/2/1065

Internet

https://www.mdpi.com/1422-0067/25/2/1065

Similar Items