Role of PKCε in the epithelial-mesenchymal transition induced by FGFR2 isoform switch
Abstract Background The epithelial isoform of the fibroblast growth factor receptor 2 (FGFR2b) controls the entire program of keratinocyte differentiation via the sequential involvement of protein kinase C (PKC) δ and PKCα. In contrast, the FGFR2 isoform switch and the aberrant expression of the mes...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12964-020-00582-1 |