Role of PKCε in the epithelial-mesenchymal transition induced by FGFR2 isoform switch

Role of PKCε in the epithelial-mesenchymal transition induced by FGFR2 isoform switch

Abstract Background The epithelial isoform of the fibroblast growth factor receptor 2 (FGFR2b) controls the entire program of keratinocyte differentiation via the sequential involvement of protein kinase C (PKC) δ and PKCα. In contrast, the FGFR2 isoform switch and the aberrant expression of the mes...

Full description

Bibliographic Details
Main Authors: Danilo Ranieri, Monica Nanni, Flavia Persechino, Maria Rosaria Torrisi, Francesca Belleudi
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Cell Communication and Signaling
Subjects:
FGFR2c
PKCε
Epithelial-mesenchymal transition
Keratinocytes
Online Access:http://link.springer.com/article/10.1186/s12964-020-00582-1

Similar Items

Similar Items