Synthesis of Substituted Oxo-Azepines by Regio- and Diastereoselective Hydroxylation

Substituted seven-membered N-heterocycles are prevalent bioactive epitopes and useful synthons for preparing enzyme inhibitors or molecular recognition systems. To fully exploit the chemical properties of this flexible N-heterocycle scaffold, efficient methods for its diverse functionalization are r...

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Bibliographic Details
Main Authors: Harold Spedding, Peter Karuso, Fei Liu
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/22/11/1871