Revisiting the Role of ß-Tubulin in Drosophila Development: β-tubulin60D is not an Essential Gene, and its Novel Pin1 Allele has a Tissue-Specific Dominant-Negative Impact

Revisiting the Role of ß-Tubulin in Drosophila Development: β-tubulin60D is not an Essential Gene, and its Novel Pin1 Allele has a Tissue-Specific Dominant-Negative Impact

Diversity in cytoskeleton organization and function may be achieved through alternative tubulin isotypes and by a variety of post-translational modifications. The Drosophila genome contains five different β-tubulin paralogs, which may play an isotype tissue-specific function in vivo. One of these ge...

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Bibliographic Details
Main Authors: Ramesh Kumar Krishnan, Naomi Halachmi, Raju Baskar, Anna Bakhrat, Raz Zarivach, Adi Salzberg, Uri Abdu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
bristle
drosophila
tissue-specific
tubulin
tubulin isotypes
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.787976/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.787976/full

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