Changes in pontine and preBötzinger/Bötzinger complex neuronal activity during remifentanil-induced respiratory depression in decerebrate dogs

Changes in pontine and preBötzinger/Bötzinger complex neuronal activity during remifentanil-induced respiratory depression in decerebrate dogs

Introduction:In vivo studies using selective, localized opioid antagonist injections or localized opioid receptor deletion have identified that systemic opioids dose-dependently depress respiratory output through effects in multiple respiratory-related brainstem areas.Methods: With approval of the s...

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Bibliographic Details
Main Authors: Barbara Palkovic, Sanda Mustapic, Ivana Saric, Eckehard A. E. Stuth, Astrid G. Stucke, Edward J. Zuperku
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Physiology
Subjects:
opioid-induced respiratory depression
respiratory control
preBötzinger complex
pontine respiratory group
respiratory pattern generator
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1156076/full

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https://www.frontiersin.org/articles/10.3389/fphys.2023.1156076/full

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