Dissection of the cell communication interactions in lung adenocarcinoma identified a prognostic model with immunotherapy efficacy assessment and a potential therapeutic candidate gene ITGB1

Dissection of the cell communication interactions in lung adenocarcinoma identified a prognostic model with immunotherapy efficacy assessment and a potential therapeutic candidate gene ITGB1

Background: The tumor microenvironment (TME) in lung adenocarcinoma (LUAD) influences tumor progression and immunosuppressive phenotypes through cell communication. We aimed to decipher cellular communication and molecular patterns in LUAD. Methods: We analyzed scRNA-seq data from LUAD patients in m...

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Bibliographic Details
Main Authors: Xing Jin, Zhengyang Hu, Jiacheng Yin, Guangyao Shan, Mengnan Zhao, Zhenyu Liao, Jiaqi Liang, Guoshu Bi, Ye Cheng, Junjie Xi, Zhencong Chen, Miao Lin
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Heliyon
Subjects:
Lung adenocarcinoma
Tumor immune microenvironment
ScRNA-seq
Immunotherapy
Prognosis
ITGB1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024126308

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http://www.sciencedirect.com/science/article/pii/S2405844024126308

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