Recurrence of the oxazole motif in tubulin colchicine site inhibitors with anti-tumor activity

Because of its wide spectrum of targets and biological activities, the oxazole ring is a valuable heterocyclic scaffold in the design of new therapeutic agents with anticancer, antiviral, antibacterial, anti-inflammatory, neuroprotective, antidiabetic and antidepressant properties. The presence of t...

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Bibliographic Details
Main Authors: Marilia Barreca, Virginia Spanò, Maria Valeria Raimondi, Chiara Tarantelli, Filippo Spriano, Francesco Bertoni, Paola Barraja, Alessandra Montalbano
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:European Journal of Medicinal Chemistry Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772417421000042