Hydrogen-bond networks for proton couplings in G-Protein coupled receptors

G-protein signaling pathways mediate communication across cell membranes. The first steps of this communication occur at the cell membrane, where upon receiving an external signal –the binding of an agonist ligand– the membrane-embedded G-Protein Coupled Receptor adopts a conformation recognized by...

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Bibliographic Details
Main Authors: Ana-Nicoleta Bondar, Mercedes Alfonso-Prieto
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Physics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2022.963716/full