New insights about the PDGF/PDGFR signaling pathway as a promising target to develop cancer therapeutic strategies

New insights about the PDGF/PDGFR signaling pathway as a promising target to develop cancer therapeutic strategies

Numerous cancers express platelet-derived growth factors (PDGFs) and PDGF receptors (PDGFRs). By directly stimulating tumour cells in an autocrine manner or by stimulating tumour stromal cells in a paracrine manner, the platelet-derived growth factor (PDGF)/platelet-derived growth factor receptor (P...

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Bibliographic Details
Main Authors: Pratibha Pandey, Fahad Khan, Tarun Kumar Upadhyay, Moon Seungjoon, Moon Nyeo Park, Bonglee Kim
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
PDGF
PDGF receptors
Cancer
Clinical trials
Signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223002792

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http://www.sciencedirect.com/science/article/pii/S0753332223002792

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