Dramatic, durable response to therapy in gBRCA2-mutated pancreas neuroendocrine carcinoma: opportunity and challenge

Abstract Poorly differentiated pancreatic neuroendocrine tumors (PDNEC), are a subtype of pancreatic cancer encompassing both small cell and large cell neuroendocrine carcinoma subtypes, and are characterized as distinct in terms of biology and prognosis compared to the more common pancreatic adenoc...

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Bibliographic Details
Main Authors: Fergus Keane, Raazi Bajwa, Pier Selenica, Wungki Park, Michael H. Roehrl, Jorge S. Reis-Filho, Diana Mandelker, Eileen M. O’Reilly
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00376-x