Characterization of Functional Human Skeletal Myotubes and Neuromuscular Junction Derived—From the Same Induced Pluripotent Stem Cell Source

In vitro generation of functional neuromuscular junctions (NMJs) utilizing the same induced pluripotent stem cell (iPSC) source for muscle and motoneurons would be of great value for disease modeling and tissue engineering. Although, differentiation and characterization of iPSC-derived motoneurons a...

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Bibliographic Details
Main Authors: Xiufang Guo, Agnes Badu-Mensah, Michael C. Thomas, Christopher W. McAleer, James J. Hickman
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/7/4/133