No increase in inflammation in late-life major depression screened to exclude physical illness

Abstract Depression is a common and debilitating disorder in the elderly. Late-life depression (LLD) has been associated with inflammation and elevated levels of proinflammatory cytokines including interleukin (IL)-1β, tumor necrosis factor-alpha, and IL-6, but often depressed individuals have comor...

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Bibliographic Details
Main Authors: Eline T. Luning Prak, Thomas Brooks, Walid Makhoul, Joanne C. Beer, Ling Zhao, Tommaso Girelli, Carsten Skarke, Yvette I. Sheline
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-01883-4