Abnormal Vacuole Membrane Protein-1 Expression in Parkinson’s Disease Patients

BackgroundParkinson’s disease (PD) is pathologically characterized by progressive dopaminergic (DAergic) neuron loss in the substantia nigra pars compacta (SNpc) and accumulation of intracytoplasmic α-synuclein-containing Lewy bodies. Autophagy has been identified as a critical component in the deve...

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Bibliographic Details
Main Authors: Murad Al-Nusaif, Cheng Cheng, Tianbai Li, Congcong Jia, Panpan Wang, Song Li, Weidong Le
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.760932/full