The Anxiolytic-like Properties of a Tryptic Hydrolysate of Bovine α<sub>s1</sub> Casein Containing α-Casozepine Rely on GABA<sub>A</sub> Receptor Benzodiazepine Binding Sites but Not the Vagus Nerve

The Anxiolytic-like Properties of a Tryptic Hydrolysate of Bovine α<sub>s1</sub> Casein Containing α-Casozepine Rely on GABA<sub>A</sub> Receptor Benzodiazepine Binding Sites but Not the Vagus Nerve

(1) Background: A tryptic hydrolysate of bovine α<sub>s1</sub>-casein (CH) exerts anxiolytic-like properties in many species, including humans. This is mainly related to the presence of α-casozepine (α-CZP), which yields these properties in rodents. This study evaluates, in a rat model,...

Full description

Bibliographic Details
Main Authors: Simon Benoit, Catherine Chaumontet, Nicolas Violle, Audrey Boulier, Zeeshan Hafeez, Céline Cakir-Kiefer, Daniel Tomé, Jessica Schwarz, Laurent Miclo
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Nutrients
Subjects:
α-casozepine
anxiolysis
casein tryptic hydrolysate
GABAA
vagotomy
Online Access:https://www.mdpi.com/2072-6643/14/11/2212

Internet

https://www.mdpi.com/2072-6643/14/11/2212

Similar Items