CD133/Src axis mediates tumor initiating property and epithelial-mesenchymal transition of head and neck cancer.

BACKGROUND:Head and Neck squamous cell carcinoma (HNSCC) is a human lethal cancer with clinical, pathological, phenotypical and biological heterogeneity. Caner initiating cells (CICs), which are responsible for tumor growth and coupled with gain of epithelial-mesenchymal transition (EMT), have been...

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Bibliographic Details
Main Authors: Yu-Syuan Chen, Meng-Ju Wu, Chih-Yang Huang, Shu-Chun Lin, Tsung-Hsien Chuang, Cheng-Chia Yu, Jeng-Fan Lo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3225383?pdf=render