Conformational Selection and Induced Fit for RNA Polymerase and RNA/DNA Hybrid Backtracked Recognition

Conformational Selection and Induced Fit for RNA Polymerase and RNA/DNA Hybrid Backtracked Recognition

RNA polymerase catalyzes transcription with a high fidelity. If DNA/RNA mismatch or DNA damage occurs downstream, a backtracked RNA polymerase can proofread this situation. However, the backtracked mechanism is still poorly understood. Here we have performed multiple explicit-solvent molecular dynam...

Cijeli opis

Bibliografski detalji
Glavni autor: Haifeng eChen
Format: Članak
Jezik:English
Izdano: Frontiers Media S.A. 2015-11-01
Serija:Frontiers in Molecular Biosciences
Teme:
Conformational selection
Induced fit
Backtracked RNA polymerase
DNA/RNA hybrid
P test
Online pristup:http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00061/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00061/full

Slični predmeti