Association of IL-17F rs2397084 (E126G), rs11465553 (V155I) and rs763780 (H161R) variants with rheumatoid arthritis and their effects on the stability of protein.

Association of IL-17F rs2397084 (E126G), rs11465553 (V155I) and rs763780 (H161R) variants with rheumatoid arthritis and their effects on the stability of protein.

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Interleukin-17F (IL-17F), considered a pro-inflammatory cytokine, has been shown to contribute to skeletal tissue degradation and hence chronic inflammation in rheumatoid arthritis (RA). In this study we utilized bioinformatics tools to analyze the effect of three exonic SNPs (rs2397084, rs11465553,...

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Bibliographic Details
Main Authors: Yasir Ali, Masood Kausar, Mazhar Farooq, Nadia Farooqi, Zia Ul Islam, Suleman Khan, Aisha Aman, Naveed Khan, Atif Kamil, Fazal Jalil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0285874&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0285874&type=printable

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