Identification of piRNA disease associations using deep learning

Identification of piRNA disease associations using deep learning

Piwi-interacting RNAs (piRNAs) play a pivotal role in maintaining genome integrity by repression of transposable elements, gene stability, and association with various disease progressions. Cost-efficient computational methods for the identification of piRNA disease associations promote the efficacy...

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Bibliographic Details
Main Authors: Syed Danish Ali, Hilal Tayara, Kil To Chong
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Sequence analysis
piRNA disease associations
Positive unlabeled learning
Reliable negative sample
Convolutional Neural Network
Deep learning
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022000666

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http://www.sciencedirect.com/science/article/pii/S2001037022000666

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