Hepatocellular carcinoma cell differentiation trajectory predicts immunotherapy, potential therapeutic drugs, and prognosis of patients

Hepatocellular carcinoma cell differentiation trajectory predicts immunotherapy, potential therapeutic drugs, and prognosis of patients

The aim of this study is to explore a novel classification and investigate the clinical significance of hepatocellular carcinoma (HCC) cells. We analyzed integrated single-cell RNA sequencing and bulk RNA-seq data obtained from HCC samples. Cell trajectory analysis divided HCC cells into three subgr...

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Bibliographic Details
Main Authors: Qiu Jun, Wang Haoyun, Lv Xin, Mao Lipeng, Huang Junyan, Hao Tao, Li Junliang, Qi Shuo, Chen Guodong, Jiang Haiping
Format: Article
Language:English
Published: De Gruyter 2023-08-01
Series:Open Life Sciences
Subjects:
cell differentiation trajectory
hepatocellular carcinoma
immune checkpoint
overall survival
molecular-targeted drugs
Online Access:https://doi.org/10.1515/biol-2022-0656

Internet

https://doi.org/10.1515/biol-2022-0656

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