Low Molecular Weight Hydroxyethyl Chitosan-Prednisolone Conjugate for Renal Targeting Therapy: Synthesis, Characterization and In Vivo Studies

<p>To further evaluate the potential renal targeting profile of low molecular weight hydroxyethyl chitosan (LMWHC) we developed before, prednisolone (Pre) was conjugated with LMWHC by EDC/NHS chemistry to improve the therapeutic effect of glucocorticoids <i>in vivo</i>. The conjuga...

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Bibliographic Details
Main Author: Xia-kai He, Zhi-xiang Yuan, Xiao-juan Wu, Chao-qun Xu, Wan-yu Li
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:Theranostics
Online Access:http://www.thno.org/v02p1054.htm