Knockout of ENO1 leads to metabolism reprogramming and tumor retardation in pancreatic cancer

The shift in glucose utilization from oxidative phosphorylation to glycolysis is the hallmark of tumor cells. The overexpression of ENO1, one of the key enzymes in the glycolysis process, has been identified in several cancers, however, its role in pancreatic cancer (PC) is yet unclear. This study i...

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Bibliographic Details
Main Authors: Qingru Song, Kai Zhang, Tianjiao Sun, Congcong Xu, Wei Zhao, Zhiqian Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1119886/full