“Redirecting an anti-IL-1β antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A”

“Redirecting an anti-IL-1β antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A”

Abstract Antibody engineering technology is at the forefront of therapeutic antibody development. The primary goal for engineering a therapeutic antibody is the generation of an antibody with a desired specificity, affinity, function, and developability profile. Mature antibodies are considered anti...

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Bibliographic Details
Main Authors: Sharon Fischman, Itay Levin, Jean-Michel Rondeau, Marek Štrajbl, Sylvie Lehmann, Thomas Huber, Guy Nimrod, Régis Cebe, Dotan Omer, Jiri Kovarik, Shmuel Bernstein, Yehezkel Sasson, Alik Demishtein, Tomer Shlamkovich, Olga Bluvshtein, Noam Grossman, Reut Barak-Fuchs, Michael Zhenin, Yair Fastman, Shir Twito, Tal Vana, Nevet Zur, Yanay Ofran
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05369-x

Internet

https://doi.org/10.1038/s42003-023-05369-x

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