Supercharged chimeric antigen receptor T cells in solid tumors
Chimeric antigen receptor (CAR) T cells have demonstrated success in treating select hematological malignancies, but their activity in solid tumors has been comparably modest. Challenges specific to treating solid tumors include trafficking and distribution throughout the tumor site, overcoming the...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Clinical Investigation
2022-08-01
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| Series: | The Journal of Clinical Investigation |
| Online Access: | https://doi.org/10.1172/JCI162322 |