Supercharged chimeric antigen receptor T cells in solid tumors

Supercharged chimeric antigen receptor T cells in solid tumors

Chimeric antigen receptor (CAR) T cells have demonstrated success in treating select hematological malignancies, but their activity in solid tumors has been comparably modest. Challenges specific to treating solid tumors include trafficking and distribution throughout the tumor site, overcoming the...

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Bibliographic Details
Main Authors:	Ayush Pant, Christopher M. Jackson
Format:	Article
Language:	English
Published:	American Society for Clinical Investigation 2022-08-01
Series:	The Journal of Clinical Investigation
Online Access:	https://doi.org/10.1172/JCI162322

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