Genetically Modified Pc 12 Brain Grafts: Survivability and Inducible Nerve Growth Factor Expression

Neural transplantation of genetically modified cells has been successfully employed to reverse functional deficits in animal models of neurodegenerative disorders, including Parkinson's disease. While implanted PC12 cells secrete dopamine in vivo and can ameliorate dopamine deficiency in parkin...

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Bibliographic Details
Main Authors: Daniel C. Rohrer, Gajanan Nilaver, Valerie Nipper, Curtis A. Machida
Format: Article
Language:English
Published: SAGE Publishing 1996-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979600500111