Spliceosome Mutations in Uveal Melanoma

Spliceosome Mutations in Uveal Melanoma

Uveal melanoma (UM) is the most common primary intraocular malignancy of the eye. It has a high metastatic potential and mainly spreads to the liver. Genetics play a vital role in tumor classification and prognostication of UM metastatic disease. One of the driver genes mutated in metastasized UM is...

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Bibliographic Details
Main Authors: Josephine Q.N. Nguyen, Wojtek Drabarek, Serdar Yavuzyigitoglu, Eva Medico Salsench, Robert M. Verdijk, Nicole C. Naus, Annelies de Klein, Emine Kiliç, Erwin Brosens
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
genetic
DNA repair
epigenetic
mutational analysis
chromosomes
prognosis
Online Access:https://www.mdpi.com/1422-0067/21/24/9546

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https://www.mdpi.com/1422-0067/21/24/9546

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