Gag-Gag Interactions Are Insufficient to Fully Stabilize and Order the Immature HIV Gag Lattice

Gag-Gag Interactions Are Insufficient to Fully Stabilize and Order the Immature HIV Gag Lattice

Immature HIV virions harbor a lattice of Gag molecules with significant ordering in CA-NTD, CA-CTD and SP1 regions. This ordering plays a major role during HIV maturation. To test the condition in which the Gag lattice forms in vivo, we assembled virus like particles (VLPs) by expressing only HIV Ga...

Full description

Bibliographic Details
Main Authors: Ipsita Saha, Benjamin Preece, Abby Peterson, Haley Durden, Brian MacArthur, Jake Lowe, David Belnap, Michael Vershinin, Saveez Saffarian
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
HIV
immature lattice
lattice dynamics
Online Access:https://www.mdpi.com/1999-4915/13/10/1946

Internet

https://www.mdpi.com/1999-4915/13/10/1946

Similar Items