Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer

Ferroptosis is a new form of regulated cell death driven by iron-dependent lipid peroxidation. Glutaminolysis and tricarboxylic acid cycle are involved in ferroptosis, but the underlying metabolic process remains unclear. We examined the role of dihydrolipoamide dehydrogenase (DLD) in ferroptosis in...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Daiha Shin, Jaewang Lee, Ji Hyeon You, Doyeon Kim, Jong-Lyel Roh
Format: Artikel
Sprache:English
Veröffentlicht: Elsevier 2020-02-01
Schriftenreihe:Redox Biology
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2213231719314351