Transforming growth factor-β1-mediated collagen gel contraction by cardiac fibroblasts

Objective Myofibroblasts and transforming growth factor-β 1 (TGF-β 1 ) are key elements of cardiac tissue fibrosis development. The aim of this study was to determine whether the ability of TGF-β 1 to affect the contractile activity of cardiac fibroblasts depends on their differentiation into myofib...

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Bibliographic Details
Main Authors: Paul Lijnen, Victor Petrov, Robert Fagard
Format: Article
Language:English
Published: SAGE Publications 2003-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2003.011