Intrathecal lidocaine pretreatment attenuates immediate neuropathic pain by modulating Nav<sub>1.3 </sub>expression and decreasing spinal microglial activation

<p>Abstract</p> <p>Background</p> <p>Intrathecal lidocaine reverses tactile allodynia after nerve injury, but whether neuropathic pain is attenuated by intrathecal lidocaine pretreatment is uncertain.</p> <p>Methods</p> <p>Sixty six adult male Sp...

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Bibliographic Details
Main Authors: Wang Hung-Chen, Wang Fu-Yuan, Lai Chung-Sheng, Cheng Kuang-I, Chang Lin-Li, Ho Shung-Tai, Tsai Hung-Pei, Kwan Aij-Li
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Neurology
Online Access:http://www.biomedcentral.com/1471-2377/11/71