ShRNA-targeted centromere protein A inhibits hepatocellular carcinoma growth.

BACKGROUND: Centromere protein A (CENP-A) plays important roles in cell-cycle regulation and genetic stability. Herein, we aimed to investigate its expression pattern, clinical significance, and biological function in hepatocellular carcinoma (HCC). METHODOLOGY/PRINCIPAL FINDINGS: CENP-A expression...

Full description

Bibliographic Details
Main Authors: Yongmei Li, Zhi Zhu, Shuhui Zhang, Danghui Yu, Hongyu Yu, Lina Liu, Xiaozhe Cao, Li Wang, Hengjun Gao, Minghua Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3058037?pdf=render