Role of NLRP3 inflammasome and oxidative stress in hepatic insulin resistance and the ameliorative effect of phytochemical intervention

Role of NLRP3 inflammasome and oxidative stress in hepatic insulin resistance and the ameliorative effect of phytochemical intervention

NLRP3 inflammasome has a key role in chronic low-grade metabolic inflammation, and its excessive activation may contribute to the beginning and progression of several diseases, including hepatic insulin resistance (hIR). Thus, this review aims to highlight the role of NLRP3 inflammasome and oxidativ...

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Bibliographic Details
Main Authors: Isabela Jesus de Deus, Ana Flávia Martins-Silva, Miliane Martins de Andrade Fagundes, Sílvia Paula-Gomes, Fernanda Guimarães Drummond e Silva, Larissa Leandro da Cruz, Aline Rezende Ribeiro de Abreu, Karina Barbosa de Queiroz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Pharmacology
Subjects:
insulin resistance
oxidative stress
reactive oxygen species
inflammasome
lowgrade inflammation
phytochemicals
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1188829/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1188829/full

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